MDMA (3,4-methylenedioxy-N-methylamphetamine) is an empathogenic drug of the phenethylamine and amphetamine classes of drugs. MDMA has become widely known as “ecstasy” (shortened to “E”, “X”, or “XTC”), usually referring to its street pill form, although this term may also include the presence of possible adulterants. However, the come down can cause depression and lethargy. As the negative effects are not well known and do not seem serious, then this drug can be seen as a safe option. It can keep you awake for many hours and this can lead to cold and sore throats being more frequent for regular users.
MDMA can induce euphoria, a sense of intimacy with others, diminished anxiety, and mild psychedelia. Many studies, particularly in the fields of psychology and cognitive therapy, have suggested has therapeutic benefits and facilitates therapy sessions in certain individuals, a practice for which it had been formally used in the past. This neurotoxic compound, unlike typical amphetamines, also suppresses locomotor activity in animals at both low and high doses. It can be easy to overdose in this situation which would mean that the negative side effects could be a lot worse as can the long term health effects,
MDMA is often known as ecstasy as well as being known by a number of other names. It is available in a pill form. The drug gives a buzz of energy and colours and sounds may feel more intense. It can also cause users to feel love and affection for people around them as well as strangers. It is possible though to feel anxious or get panic attacks and in some cases paranoia or psychosis can occur. It can take a while to take effect and it can be tempting or some people to then take an extra tablet as they think it is not working and then if both work together it can cause much more intense effects.
MDMA is member of the drug class opioid analgesics. Specifically U47700 belongs to the benzamide class of opioids. It is not used medically but within scientific research. U-47700 has the systematic and formal IUPAC name 3,4-Dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide. It has a molar mass of 329.27 grams and an empirical chemical formula of C16H22Cl2N2O.
It was first developed by a team of researchers at the pharmaceutical firm Upjohn in the late 1970s. In animal models U47700 was shown to have potency 7.5 times greater than the classical medicinal opiate morphine. Pharmacologically U47700 is a selective agonist at the opioid receptor with a Kd of 5.3 nM in contrast to a much weaker binding interaction at the kappa opioid receptor where U47700 have a Kd value of 910 nM. U47700 is a structural analogue of an earlier opioid AH-7921.
When discussing the topic of research chemicals and their designer drug counter part “bath salts” there is myth, truth and out right lies being marketed to everyone that has come into contact with this subject. The general media has once again taken a real issue to an almost laughable extreme.